PIC1 PA
Based on 1 Customer Validation
PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region (CLR) of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant (KD) of 33.3 nM.
For research use only. We do not sell to patients.
- Purity: 98.37%
- CAS No.: 1356469-36-7
- Formula: C71H123N19O21S2
- Molecular Weight:1642.98
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1356469-36-7
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Appearance Solid
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Molecular Weight 1642.98
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Formula C71H123N19O21S2
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Color White to off-white
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Sequence
Ile-Ala-Leu-Ile-Leu-Glu-Pro-Ile-Cys-Cys-Gln-Glu-Arg-Ala-Ala
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Sequence Shortening
IALILEPICCQERAA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (60.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6087 mL | 3.0433 mL | 6.0865 mL | 15.2163 mL |
| 5 mM | 0.1217 mL | 0.6087 mL | 1.2173 mL | 3.0433 mL | |
| 10 mM | 0.0609 mL | 0.3043 mL | 0.6087 mL | 1.5216 mL | |
| 15 mM | 0.0406 mL | 0.2029 mL | 0.4058 mL | 1.0144 mL | |
| 20 mM | 0.0304 mL | 0.1522 mL | 0.3043 mL | 0.7608 mL | |
| 25 mM | 0.0243 mL | 0.1217 mL | 0.2435 mL | 0.6087 mL | |
| 30 mM | 0.0203 mL | 0.1014 mL | 0.2029 mL | 0.5072 mL | |
| 40 mM | 0.0152 mL | 0.0761 mL | 0.1522 mL | 0.3804 mL | |
| 50 mM | 0.0122 mL | 0.0609 mL | 0.1217 mL | 0.3043 mL | |
| 60 mM | 0.0101 mL | 0.0507 mL | 0.1014 mL | 0.2536 mL |
PIC1 PA Related Classifications
HY-P10827 Related Classifications
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