2 Results for "

Compound E (GMP)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Compound E (GMP)" in MCE Product Catalog:

Cat. No.: HY-14176G
CAS No.: 209986-17-4
Synonyms: γ-Secretase-IN-1 (GMP)
Compound E (GMP) is a GMP-grade Compound E (HY-14176). GMP-grade small molecules can be used as adjuvant reagents in cell therapy. Compound E is a γ-secretase inhibitor. Compound E inhibits β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50 values ​​of 0.24, 0.37, and 0.32 nM, respectively .
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Cat. No.: HY-155337
Research Areas:  

Cancer

eIF4E-IN-6(compound 4b) is a GMP analogs synthesized to targeteIF4Eand restrain its binding to cap mRNA.eIF4E-IN-6shows cell cytotoxicity against Caco-2, HepG-2,and MCF-7 cells, withIC50values of 31, 27, and 21 μM, respectively .
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