3 Results for "

Conglobatin

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Conglobatin" in MCE Product Catalog:

Cat. No.: HY-119906
CAS No.: 72263-05-9
Purity:  95.48%
Synonyms: FW-04-806
Conglobatin (FW-04-806), a macrolide dilactone, is isolated from the culture of Streptomyces conglobatus. Conglobatin is an orally active Hsp90 inhibitor. Conglobatin can bind to the N-terminal domain of Hsp90 and disrupt Hsp90-Cdc37 complex formation. Conglobatin induces apoptosis in human breast cancer cells and esophageal squamous cell carcinoma cells, and exhibits antitumor activity in vivo .
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Cat. No.: HY-172745
CAS No.: 3053775-15-5
Target:  

Others

Conglobatin B1 is a compound that can be isolated from Australian Streptomyces MST-91080. Conglobatin B1 is cytotoxic to the NS-1 myeloma cell line with an IC50 of 0.084 μg/mL, but has low toxicity to NFF human fibroblasts. Conglobatin B1 can be used in the study of cancer .
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Cat. No.: HY-158925
CAS No.: 2673270-37-4
Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC50 = 1.05 μg/mL) .
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