Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
DDR1-IN-2
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "DDR1-IN-2" in MCE Product Catalog:
6
Target:
Research Areas:
7rh (DDR1-IN-2) is a potent inhibitor of discoidin domain receptor 1 (DDR1), with an IC50 of 13.1 nM, and also less potently inhibits DDR2, with an IC50 of 203 nM. 7rh is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target:
Research Areas:
DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases .
Cat. No.: HY-187093
CAS No.: 3076856-56-6
Synonyms: DDR1-IN-2-Boc
Research Areas:
7rh-Boc (DDR1-IN-2-Boc) is a DDR1 ligand that can be used for the synthesis of ATTECs, such as LLC355 (HY-162540) .
Cat. No.: HY-187094
CAS No.: 3076856-77-1
Synonyms: DDR1-IN-2-C2-O-Boc
Research Areas:
7rh-C2-O-Boc (DDR1-IN-2-C2-O-Boc) is a DDR1 ligand and linker conjugate that can be used for the synthesis of ATTECs, such as LLC355 (HY-162540) .
Cat. No.: HY-181754
CAS No.: 1005781-50-9
Target:
Research Areas:
TPKI-39 is a DDR1, DDR2, and FLT1 inhibitor, with a human DDR1 IC50 of 380 nM, human DDR1 Ka of 24 nM, human DDR2 IC50 of 120 nM, human FLT1 IC50 of 65 nM, and human FLT1 Ka of 91 nM.TPKI-39 inhibits DDR1 enzymatic activity and autophosphorylation, DDR2 enzymatic activity, and FLT1 enzymatic activity in cells.TPKI-39 inhibits collagen-induced DDR1 autophosphorylation in cells .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
