DDR1/2 inhibitor-2
Based on 1 Customer Validation
DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC50 values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases.
For research use only. We do not sell to patients.
- Purity: 99.73%
- CAS No.: 2908756-11-4
- Formula: C25H19F3N6O2
- Molecular Weight:492.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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DDR1 |
DDR2 |
Chemical Information
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CAS No. 2908756-11-4
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Appearance Solid
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Molecular Weight 492.45
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Formula C25H19F3N6O2
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Color White to off-white
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SMILES
O=C(CN1C=CC2=C(C1=O)C(NC3=CC(C=NN4C)=C4C=C3)=CC=C2)NC5=CN=CC(C(F)(F)F)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 16.67 mg/mL (33.85 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0307 mL | 10.1533 mL | 20.3066 mL | 50.7666 mL |
| 5 mM | 0.4061 mL | 2.0307 mL | 4.0613 mL | 10.1533 mL | |
| 10 mM | 0.2031 mL | 1.0153 mL | 2.0307 mL | 5.0767 mL | |
| 15 mM | 0.1354 mL | 0.6769 mL | 1.3538 mL | 3.3844 mL | |
| 20 mM | 0.1015 mL | 0.5077 mL | 1.0153 mL | 2.5383 mL | |
| 25 mM | 0.0812 mL | 0.4061 mL | 0.8123 mL | 2.0307 mL | |
| 30 mM | 0.0677 mL | 0.3384 mL | 0.6769 mL | 1.6922 mL |