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Cat. No.: HY-187094

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7rh-C2-O-Boc

(Synonyms: DDR1-IN-2-C2-O-Boc)

7rh-C2-O-Boc (DDR1-IN-2-C2-O-Boc) is a DDR1 ligand and linker conjugate that can be used for the synthesis of ATTECs, such as LLC355 (HY-162540).

For research use only. We do not sell to patients.

CAS No.: 3076856-77-1
Formula: C₃₇H₄₁F₃N₆O₄
Molecular Weight:690.75

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

7rh-C2-O-Boc Chemical Structure

CAS No.: 3076856-77-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
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Biological Activity

Description

7rh-C2-O-Boc (DDR1-IN-2-C2-O-Boc) is a DDR1 ligand and linker conjugate that can be used for the synthesis of ATTECs, such as LLC355 (HY-162540)^[1].

IC₅₀ & Target^[1]

DDR1

All Discoidin Domain Receptor Isoforms :

DDR1
DDR2

Chemical Information

CAS No. 3076856-77-1
Molecular Weight 690.75
Formula C₃₇H₄₁F₃N₆O₄
SMILES

O=C(C1=CC(C#CC(C=N2)=CN3C2=CC=N3)=C(CC)C=C1)NC4=CC(CN(CC5)CCN5CCOCC(OC(C)(C)C)=O)=CC(C(F)(F)F)=C4
Synonyms

DDR1-IN-2-C2-O-Boc
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liu L, et al. Discovery of as an Autophagy-Tethering Compound for the Degradation of Discoidin Domain Receptor 1. Journal of medicinal chemistry. 2024 May 23;67(10):8043-8059. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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7rh-C2-O-Boc

All Discoidin Domain Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

7rh-C2-O-Boc Related Classifications

HY-187094 Related Classifications