2 Results for "

DK-221

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DK-221" in MCE Product Catalog:

Cat. No.: HY-P11888
CAS No.: 1886065-39-9
Target:  

PD-1/PD-L1

Research Areas:  

Cancer

DK 221 is a PD-L1 blocker with an IC50 of 24.5 nM for inhibiting the binding of PD-L1 to PD-1. DK 221 reduces the uptake of [ 18F]DK222 in PD-L1-positive tumor cells and mouse xenografts. DK 221 is applicable to research related to triple-negative breast cancer and melanoma .
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Cat. No.: HY-164576
CAS No.: 1374994-81-6
Synonyms: NODA-Bz-SCN
Research Areas:  

Cancer

NCS-MP-NODA (NODA-Bz-SCN) is a NODA-derived bifunctional chelator. NCS-MP-NODA can conjugate with biomolecules including the RGD tripeptide, and is used for aluminum-[ 18F] fluoride-based positron emission tomography (PET) radiolabeling. NCS-MP-NODA can conjugate with the free lysine amino group of the PD-L1-specific peptide DK221 to generate DK222, which can be radiolabeled with 18F to form [ 18F]DK222. NCS-MP-NODA can be used in studies related to triple-negative breast cancer, melanoma and colon cancer .
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