2 Results for "

DMP728

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "DMP728" in MCE Product Catalog:

Cat. No.: HY-167848
CAS No.: 153345-74-5
Synonyms: XL-118
Target:  

Others

Research Areas:  

Cardiovascular Disease

DMP-728 free base (XL-118) is a highly potent and selective GPIIb/IIIa antagonist with antiplatelet and antithrombotic activities. DMP-728 free base can inhibit ADP-induced human platelet aggregation in vitro, with an IC50 of 46 nmol/L, and can significantly reduce the interaction between fibrinogen and human platelets or Binding of purified human GPIIb/IIIa receptors. DMP-728 free base exhibits dose-dependent antiplatelet effects in anesthetized mongrel dogs, effectively inhibiting ADP-induced platelet aggregation and prolonging template bleeding time .
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Cat. No.: HY-125615
CAS No.: 155158-97-7
Target:  

Glycoprotein VI

Research Areas:  

Cardiovascular Disease Others

DMP 728 methanesulfonate is a platelet glycoprotein (GP) IIb/IIIa receptor antagonist. DMP 728 methanesulfonate shows dose-dependent antiplatelet and antithrombotic effects. DMP 728 methanesulfonate can be used in the study of effective antithrombotic agents in thromboembolic diseases of coronary and peripheral arteries .
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