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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
DOT1L808
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "DOT1L808" in MCE Product Catalog:
Cat. No.: HY-181789
Target:
Research Areas:
DOT1L808 is a potent and highly selective DOT1L PROTAC degrader with a DC50 value of 5 nM. DOT1L808 can promote the ubiquitination and degradation of DOT1L. DOT1L808 exhibits antitumor activity in an orthotopic leukemia model .
Cat. No.: HY-181748
Research Areas:
VHL Ligand-Linker Conjugates 18 is an E3 ligase ligand-linker conjugate containing an E3 ligase ligand (HY-181791) and a linker. VHL Ligand-Linker Conjugates 18 can be used for the synthesis of PROTACs, such as DOT1L808 (HY-181789) .
Cat. No.: HY-181790
Research Areas:
DOT1L ligand-2 (Compound 52) is a DOT1L ligand. DOT1L ligand-2 acts as a Ligand for Target Protein for PROTAC, which is used to develop and design degraders of PROTAC DOT1L, such as DOT1L808 (HY-181789). DOT1L ligand-2 is applicable to research related to MLL-rearranged leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
