3 Results for "

DR4 ligand

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "DR4 ligand" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99934
CAS No.: 1820660-69-2
Synonyms: ABBV-621

Research Areas:  

Cancer

Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .
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Cat. No.: HY-120794
CAS No.: 182134-00-5
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC50 of 50 nM. SC 67655 can be used for the study of autoimmune diseases .
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Cat. No.: HY-P87404A
Synonyms: CD261, APO2, DR4, TRAILR1, TNFRSF10A, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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