1 Result for "

DS5272

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DS5272" in MCE Product Catalog:

Cat. No.: HY-120667
CAS No.: 1235575-97-9
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

DS-5272 is an orally acitve inhibitor for p53-MDM2 with an IC50 of 20 nM. DS-5272 inhibits the proliferation of SJSA-1 (wildtype p53, IC50=0.17 μM) and DLD-1 (mutant p53). DS-5272 arrest the cell cycle, and induces apoptosis in SJSA-1. DS-5272 exhibits antitumor efficacy in mice .
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