1 Result for "

DW34

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "DW34" in MCE Product Catalog:

Cat. No.: HY-173564
CAS No.: 2758171-54-7
DW34 is an orally active pan-BRD4-D1 biased inhibitor with additional BRD4-D2 inhibitive activity. DW34 displays comparable inhibitive efficacy to I-BET151 (HY-13235) (EC50 = 0.16 μM) with low nanomolar EC50 values of 0.14 μM. DW34 significantly reduces liver inflammation induced by LPS (HY-D1056) and APAP (HY-66005) via reducing chemokine expression and cellular necrosis .
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