2 Results for "

Dimethyl isosorbide

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Dimethyl isosorbide" in MCE Product Catalog:

Cat. No.: HY-134524
CAS No.: 5306-85-4
Purity:  99.64%
Synonyms: Dimethyl isosorbide; O,O-Dimethylisosorbide
Research Areas:  

Others

Isosorbide dimethyl ether (Dimethyl isosorbide) is a bio-based green solvent. Isosorbide dimethyl ether is used for the preparation of sustainable ultrafiltration and microfiltration membranes. Isosorbide dimethyl ether can serve as an eco-friendly eluent for liquid chromatography. When used as a liquid chromatography mobile phase at a ratio of 50% (v/v) under 40 °C, with a system back pressure of 160-300 bar and an ultraviolet cutoff wavelength of 240 nm, Isosorbide dimethyl ether enables the quantitative analysis of Methylparaben (HY-W016806) and Propylparaben (HY-N2026) in biological preparations .
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Cat. No.: HY-183326
CAS No.: 2013542-44-2
Synonyms: IDMF
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

Isosorbide di-(methyl fumarate) (IDMF), topical DMF (HY-17363) derivative, is an NRF2/ARE pathway activator. Isosorbide di-(methyl fumarate) downregulates ANCR targets, modulates epithelial differentiation, represses proinflammatory cytokine genes, IL-17A- and TNF-induced keratinocyte genes, psoriatic skin lesion-specific genes, and immune response genes. Isosorbide di-(methyl fumarate) stimulates oxidative stress response gene transcription, reduces erythema and scaling in Imiquimod (HY-B0180)-induced psoriasiform lesions. Isosorbide di-(methyl fumarate) exhibits no genotoxicity or radiation sensitivity in skin fibroblasts, is nonirritating and nonsensitizing in rodent models. Isosorbide di-(methyl fumarate) can be used for the research of psoriasis vulgaris .
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