5306-85-4
Chemical Structure
Isosorbide dimethyl ether
Synonym(s): Dimethyl isosorbide; O,O-Dimethylisosorbide
- CAS No.: 5306-85-4
- Formula:C8H14O4
- Molecular Weight:174.19
IUPAC Name: (3R,3aR,6S,6aR)-3,6-dimethoxyhexahydrofuro[3,2-b]furan
InChIKey: MEJYDZQQVZJMPP-ULAWRXDQSA-N
SMILES: [H][C@]1(OC[C@@H]2OC)[C@]2([H])OC[C@H]1OC
Biological Activity: Isosorbide dimethyl ether (Dimethyl isosorbide) is a bio-based green solvent. Isosorbide dimethyl ether is used for the preparation of sustainable ultrafiltration and microfiltration membranes. Isosorbide dimethyl ether can serve as an eco-friendly eluent for liquid chromatography. When used as a liquid chromatography mobile phase at a ratio of 50% (v/v) under 40 °C, with a system back pressure of 160-300 bar and an ultraviolet cutoff wavelength of 240 nm, Isosorbide dimethyl ether enables the quantitative analysis of Methylparaben (HY-W016806) and Propylparaben (HY-N2026) in biological preparations[1][2][3].
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Isosorbide dimethyl ether | 99.64% | Isosorbide dimethyl ether (Dimethyl isosorbide) is a bio-based green solvent. Isosorbide dimethyl ether is used for the preparation of sustainable ultrafiltration and microfiltration membranes. Isosorbide dimethyl ether can serve as an eco-friendly eluent for liquid chromatography. When used as a liquid chromatography mobile phase at a ratio of 50% (v/v) under 40 °C, with a system back pressure of 160-300 bar and an ultraviolet cutoff wavelength of 240 nm, Isosorbide dimethyl ether enables the quantitative analysis of Methylparaben (HY-W016806) and Propylparaben (HY-N2026) in biological preparations. | ||||||||||||||||||||
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- [1]. Russo F, et al. Dimethyl isosorbide as a green solvent for sustainable ultrafiltration and microfiltration membrane preparation[J]. ACS Sustainable Chemistry & Engineering, 2020, 8(1): 659-668.
- [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2016 May 25;87:88-99. [Content Brief]
- [3]. Damjanoska A, et al. Dimethyl Isosorbide: An Innovative Bio-Renewable Solvent for Sustainable Chromatographic Applications. Molecules (Basel, Switzerland). 2025 Jun 24;30(13):2713. [Content Brief]
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