4 Results for "

E6007

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "E6007" in MCE Product Catalog:

161
161 Cited Publications
Cat. No.: HY-16749A
CAS No.: 2040295-03-0
Synonyms: PLX-3397 hydrochloride
Target:  

c-Fms c-Kit Apoptosis

Research Areas:  

Cancer

Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity .
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Cat. No.: HY-109151
CAS No.: 859217-52-0
Purity:  99.94%
Synonyms: E6007
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of <5 μM .
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Cat. No.: HY-109151R
CAS No.: 859217-52-0
Synonyms: E6007 (Standard)
Research Areas:  

Inflammation/Immunology

Milategrast (Standard) is the analytical standard of Milategrast (HY-109151). This product is intended for research and analytical applications. Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of <5 μM .
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Cat. No.: HY-16749AR
CAS No.: 2040295-03-0
Synonyms: PLX-3397 hydrochloride (Standard)
Research Areas:  

Cancer

Pexidartinib (hydrochloride) (Standard) is the analytical standard of Pexidartinib (hydrochloride). This product is intended for research and analytical applications. Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity .
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