2 Results for "

EME1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "EME1" in MCE Product Catalog:

Cat. No.: HY-RS04346
Research Areas:  

Others

EME1 Human Pre-designed siRNA Set A contains three designed siRNAs for EME1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-181840
CAS No.: 1846587-13-0
Target:  

Endonuclease

Research Areas:  

Cancer

MU262 is a MUS81 inhibitor with an IC50 value of 0.87 μM. MU262 directly inhibits the catalytic activity of MUS81 without interfering with DNA binding, induces genomic instability in tumor cells, and specifically inhibits the HR/BIR repair pathway. The combination of MU262 with Cisplatin (HY-17394) significantly enhances the chemotherapeutic killing effect. MU262 serves as a chemical biology tool for studying MUS81 function, and also acts as a lead compound for the development of anticancer therapies that exploit DNA repair defects in cancer cells [1].
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