Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
ESKAPE strains
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "ESKAPE strains" in MCE Product Catalog:
Cat. No.: HY-155007
Purity: 99.77%
DNA gyrase B-IN-2 (Compound E) is a 2-aminobenzothiazole-based DNA gyrase B inhibitor with promising activity against ESKAPE bacterial pathogens. DNA gyrase B-IN-2 showed low nanomolar inhibition of DNA gyrase (IC50 < 10 nM) and broad-spectrum antibacterial activity against pathogens belonging to the ESKAPE group, with the minimum inhibitory concentration < 0.03 μg/mL for most Gram-positive strains and 4–16 μg/mL against Gram-negative E. coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae.DNA gyrase B-IN-2 can be used for the research of infection .
Cat. No.: HY-187213
Research Areas:
Anti-MRSA agent 45 is a dihydrofolate reductase (DHFR) inhibitor and membrane-disrupting agent. Anti-MRSA agent 45 disrupts MRSA membrane integrity, increases membrane permeability and induces bacterial morphological damage. Anti-MRSA agent 45 exerts rapid, time- and concentration-dependent bactericidal activity against MRSA, and inhibits MRSA biofilm formation. Anti-MRSA agent 45 is applicable to research related to MRSA infection .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
