1 Result for "

EV206

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EV206" in MCE Product Catalog:

Cat. No.: HY-168566
CAS No.: 2247047-81-8
Target:  

HSP

Research Areas:  

Cancer

EV206 is a Hsp70 binder and apoptosis inducer that binds to the N-terminal domain of Hsp70, promotes Hsp70 degradation via the ubiquitin-proteasome system, and reduces Hsp70 protein stability. EV206 induces apoptotic cell death, inhibits colony formation, and downregulates the expression of cancer stem cell-related markers in non-small cell lung cancer cells. EV206 inhibits the growth of H460 xenograft tumors in nude mice and can be used for the research of non-small cell lung cancer .
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