7 Results for "

Eplerenone

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Eplerenone" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-B0251
CAS No.: 107724-20-9
Synonyms: Epoxymexrenone
Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
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Cat. No.: HY-B0251R
CAS No.: 107724-20-9
Synonyms: Epoxymexrenone (Standard)
Eplerenone (Standard) is the analytical standard of Eplerenone. This product is intended for research and analytical applications. Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
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Cat. No.: HY-B0251S
Synonyms: Epoxymexrenone-d3
Eplerenone-d3 is the deuterium labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, competitive and oreally active aldosterone antagonist with an IC50 of 138 nM. Eplerenone has low affinity for progesterone, androgen, estrogen and glucocorticoid receptors. Eplerenone can be used for hypertension and heart failure after myocardial infarction reserch .
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Cat. No.: HY-B0251S1
Synonyms: Epoxymexrenone-13C,d3
Eplerenone- 13C,d3 (Epoxymexrenone- 13C,d3) is 13C labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
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Cat. No.: HY-137396
CAS No.: 209253-80-5
Target:  

Endogenous Metabolite

Research Areas:  

Cardiovascular Disease

6β-Hydroxy Eplerenone is a metabolite of Eplerenone (HY-B0251). 6β-Hydroxy Eplerenone plays an important role in the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
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Cat. No.: HY-W749323
CAS No.: 334678-67-0
Research Areas:  

Cardiovascular Disease

21-Hydroxyeplerenone is a major metabolite of the mineralocorticoid receptor antagonist Eplerenone (HY-B0251). 21-Hydroxyeplerenone is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.
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Cat. No.: HY-W105644R
CAS No.: 95716-70-4
Synonyms: Δ9,11-Eplerenone (Standard)
Target:  

Reference Standards

(2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate (Standard) is the analytical standard of (2'R,7R,8R,10S,13S,14S)-Methyl 10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,10,12,13,14,15,16-tetradecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-carboxylate. This product is intended for research and analytical applications.
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