1 Result for "

FSP1-knockout

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FSP1-knockout" in MCE Product Catalog:

33
33 Cited Publications
Cat. No.: HY-136057
CAS No.: 150651-39-1
Purity:  99.96%
Research Areas:  

Cancer

iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3 (HY-100218A) [1].
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