1 Result for "

Ferroptosis inducer 12

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Ferroptosis inducer 12" in MCE Product Catalog:

Cat. No.: HY-178370
Research Areas:  

Cancer

Ferroptosis inducer-12 is a potent and selective ferroptosis inducer. Ferroptosis inducer-12 exhibits potent antiproliferative activity against HT1080 and OS-RC-2, with IC50 values of 3 nM and 5 nM, respectively. Ferroptosis inducer-12 strongly inhibits GPX4 enzymatic activity, induces intracellular ROS and elevates intracellular Fe 2+ levels in OS-RC-2 cells. Ferroptosis inducer-12 significantly inhibits tumor growth in BALB/c nude mice bearing OS-RC-2 xenografts. Ferroptosis inducer-12 can be used for the study of cancer .
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