2 Results for "

Filgotinib (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Filgotinib (Standard)" in MCE Product Catalog:

Cat. No.: HY-18300R
CAS No.: 1206161-97-8
Synonyms: GLPG0634 (Standard)
Target:  

Reference Standards JAK

Research Areas:  

Cancer

Filgotinib (Standard) is the analytical standard of Filgotinib. This product is intended for research and analytical applications. Filgotinib (GLPG0634) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
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Cat. No.: HY-18300AR
CAS No.: 1802998-75-9
Synonyms: GLPG0634 maleate (Standard)
Research Areas:  

Inflammation/Immunology

Filgotinib (maleate) (Standard) is the analytical standard of Filgotinib (maleate). This product is intended for research and analytical applications. Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib maleate can effectively inhibit the activities of JAK1, JAK2, JAK3 and TYK2 with IC50 values ​​of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib maleate also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib maleate can be used in the study of rheumatoid arthritis and inflammatory bowel disease .
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