Filgotinib (Standard)
Based on 1 Customer Validation
Filgotinib (Standard) is the analytical standard of Filgotinib. This product is intended for research and analytical applications. Filgotinib (GLPG0634) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.56%
- No. CAS: 1206161-97-8
- Fòrmula: C21H23N5O3S
- Peso molecular:425.50
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-18300
FilgotinibJAK1 Inhibitor -
HY-15315
BaricitinibJAK1/2 Inhibitor -
HY-50856
RuxolitinibJAK1/2 Inhibitor -
HY-40354
TofacitinibJAK1/JAK3 Inhibitor -
HY-117287
DeucravacitinibTYK2 Inhibitor -
HY-19569
UpadacitinibJAK1 Inhibitor -
HY-10409
FedratinibJAK2 Inhibitor -
HY-10193
AZD-1480JAK1/2 Inhibitor -
HY-40354A
Tofacitinib citrateJAK1/JAK3 Inhibitor -
HY-15270
BMS-911543JAK2 Inhibitor -
HY-15315R
Baricitinib (Standard)JAK1/2 Inhibitor -
HY-50856R
Ruxolitinib (Standard)JAK1/2 Inhibitor
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 1206161-97-8
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Appearance Solid
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Peso molecular 425.50
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Fòrmula C21H23N5O3S
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Color White to off-white
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SMILES
O=C(C1CC1)NC2=NN3C(C4=CC=C(CN5CCS(CC5)(=O)=O)C=C4)=CC=CC3=N2
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Synonyms
GLPG0634 (Standard)
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Van Rompaey L, et al. Preclinical characterization of GLPG0634, a selective inhibitor of JAK1, for the treatment of inflammatory diseases. J Immunol. 2013, 191(7), 3568-3577. [Content Brief]
[2]. Menet CJ, et al. Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634. J Med Chem. 2014 Nov 17. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Filgotinib (Standard) Related Classifications
HY-18300R Related Classifications
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