1 Result for "

GFB8438

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GFB8438" in MCE Product Catalog:

Cat. No.: HY-133012
CAS No.: 2304549-73-1
Purity:  99.74%
Target:  

TRP Channel

Research Areas:  

Neurological Disease

GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model .
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