1 Result for "

GIGA564

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GIGA564" in MCE Product Catalog:

Cat. No.: HY-P991958

Target:  

CTLA-4

Research Areas:  

Cancer

GIGA-564 is a fully human anti-CTLA4 IgG1 monoclonal antibody with a Kd of 9.8 nM. GIGA-564 binds to a unique epitope of CTLA-4, mediates FcR-dependent signaling pathways, depletes CTLA-4-highly-expressing regulatory T cells within tumors, and inhibits the proliferation of peripheral regulatory T cells. GIGA-564 exhibits anti-tumor activity in mouse models. GIGA-564 can be used for tumor research .
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