1 Result for "

GMA839

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GMA839" in MCE Product Catalog:

Cat. No.: HY-117955
CAS No.: 162882-76-0
Synonyms: WAY 141839; Co 2-6749
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

GMA-839 is a selective modulator of the γ-aminobutyric acid A receptor (GABAA) with an IC50 value of 230 nM. GMA-839 exhibits potent anxiolytic-like activity, demonstrating significant dose-dependent anxiolytic effects in animal models, with an effective oral dose of 1.6 mg/kg. Significant increases in punished responding were observed in squirrel monkeys and pigeons. GMA-839 shows promise for research in the field of anxiolytics .
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