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GMQ

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-107757
    GMQ hydrochloride

    2-Guanidine-4-methylquinazoline hydrochloride

    		 Sodium Channel Neurological Disease
    GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .
    GMQ hydrochloride
  • HY-139226
    GMQ

    2-Guanidine-4-methylquinazoline

    		 GABA Receptor Inflammation/Immunology
    GMQ is an acid-sensing ion channel modulator, competitive GABAAR antagonist. GMQ preferentially, potently, competitively inhibits GABAARs. GMQ inhibits α1β2, α1β2γ2, α4β2γ2 and α5β2γ2 GABAARs. GMQ enhances neuronal excitation through inhibition of GABAergic transmission. GMQ has anti-histamine effects in the enteric system, inhibiting gastric acid secretion .
    GMQ
  • HY-107757R
    GMQ hydrochloride (Standard)

    2-Guanidine-4-methylquinazoline hydrochloride (Standard)

    		 Reference Standards Sodium Channel Neurological Disease
    GMQ hydrochloride (Standard) is the analytical standard of GMQ (hydrochloride) (HY-107757). This product is intended for research and analytical applications. GMQ (hydrochloride) is a ASIC (acid-sensing ion) channel activator with an EC50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ (hydrochloride) opens only ASIC3 but no other ASICs at pH 7.4. GMQ (hydrochloride) can be used for neurological disease research .
    GMQ hydrochloride (Standard)

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