2 Results for "

GS 829845

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "GS 829845" in MCE Product Catalog:

Cat. No.: HY-W394903
CAS No.: 1257705-09-1
Target:  

Drug Metabolite JAK

Research Areas:  

Inflammation/Immunology

GS-829845 is a is a major, active metabolite of Filgotinib (HY-18300). GS-829845 is a JAK1 preferential inhibitor but is approximately 10-fold less potent than the parent and with a longer half-life .
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Cat. No.: HY-W394903R
CAS No.: 1257705-09-1
Isatin (Standard) is the analytical standard of Isatin. This product is intended for research and analytical applications. Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 of 3 μM. Also binds to central benzodiazepine receptors (IC50 against clonazepam, 123 μM) . Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity . Shows effect on the serotonergic system .
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