1257705-09-1
1257705-09-1
Chemical Structure
GS-829845
- CAS No.: 1257705-09-1
- Formula:C17H19N5O2S
- Molecular Weight:357.43
IUPAC Name: 3-(5-((2-ethyl-1H-imidazol-1-yl)methyl)-1,2,4-oxadiazol-3-yl)benzaldehyde
InChIKey: BYWJAVQGRJEEHH-UHFFFAOYSA-N
SMILES: O=S1(CCN(CC1)CC2=CC=C(C3=CC=CC4=NC(N)=NN43)C=C2)=O
Biological Activity: GS-829845 is a is a major, active metabolite of Filgotinib (HY-18300). GS-829845 is a JAK1 preferential inhibitor but is approximately 10-fold less potent than the parent and with a longer half-life[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GS-829845 | 99.19% | GS-829845 is a is a major, active metabolite of Filgotinib (HY-18300). GS-829845 is a JAK1 preferential inhibitor but is approximately 10-fold less potent than the parent and with a longer half-life. | ||||||||||||||||||||
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GS-829845 (Standard) | ≥98% | Isatin (Standard) is the analytical standard of Isatin. This product is intended for research and analytical applications. Isatin (Indoline-2,3-dione) is a potent inhibitor of monoamine oxidase (MAO) with an IC50 of 3 μM. Also binds to central benzodiazepine receptors (IC50 against clonazepam, 123 μM). Also acts as an antagonist of both atrial natriuretic peptide stimulated and nitric oxide-stimulated guanylate cyclase activity. Shows effect on the serotonergic system. | ||||||||||||||||||||
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References
Keywords
