3 Results for "

GSK690693

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "GSK690693" in MCE Product Catalog:

  • Targets Recommended:
42
42 Cited Publications
Cat. No.: HY-10249
CAS No.: 937174-76-0
Purity:  98.47%
Target:  

Akt AMPK Autophagy

Research Areas:  

Cancer

GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation .
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Cat. No.: HY-10249R
CAS No.: 937174-76-0
Research Areas:  

Cancer

GSK-690693 (Standard) is the analytical standard of GSK-690693 (HY-10249). This product is intended for research and analytical applications. GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation .
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Cat. No.: HY-161891
Target:  

EGFR Akt

Research Areas:  

Cancer

EGFR/Akt-IN-1 (compound 17) is a potent inhibitor of EGFR/Akt, with the IC50s of 12.89 μM and 10.88 μM in A549 cells, respectively. EGFR/Akt-IN-1 arrestes the cell cycle at the S phase .
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