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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Gefitinib-based PROTAC 3
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Gefitinib-based PROTAC 3" in MCE Product Catalog:
4
4 Cited Publications
Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively .
Cat. No.: HY-184548
CAS No.: 2230825-01-9
Research Areas:
(S,R,S)-AHPC-CO-PEG2-C5-TsO is an E3 ligase ligand-linker conjugate that can be used to synthesize Gefitinib-based PROTAC 3 (HY-123921).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
