1 Result for "

H3K18la

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "H3K18la" in MCE Product Catalog:

Cat. No.: HY-N2126
CAS No.: 952068-57-4
Parishin E is a modulator of hexokinase 2, lactate dehydrogenase A, and silent information regulator 6 (sirtuin 6), and is also a component present in Gastrodia elata Blume . Parishin E reduces the expression of hexokinase 2 and lactate dehydrogenase A, thereby regulating the process of cellular glycolysis . Parishin E regulates the deacetylation mediated by silent information regulator 6 (Sirtuin 6), and inhibits histone 3 lactylation modifications at the H3K18la and H3K27la sites . Parishin E inhibits macrophage polarization . Parishin E alleviates LPS-induced inflammatory responses and suppresses the expression of pro-inflammatory cytokines . Parishin E exerts ameliorating effects on rheumatoid arthritis . Parishin E can be used in studies related to rheumatoid arthritis .
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