1 Result for "

HBT1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HBT1" in MCE Product Catalog:

Cat. No.: HY-122742
CAS No.: 489408-02-8
Purity:  99.83%
Target:  

iGluR

Research Areas:  

Neurological Disease

HBT1 is an effective AMPA receptor AMPA-R potentiator. HBT1 specifically binds to the ligand-binding domain (LBD) of AMPAR and enhances receptor activity only when AMPA is present., HBT1 has almost no agonistic effect (i.e., reaching the optimal concentration, and then the efficacy decreases as the concentration continues to increase) compared with traditional AMPA-R potentiator, avoiding the bell-shaped reaction of brain-derived neurotrophic factor (BDNF) production in primary neurons. HBT1 can be applicable to a wider range of neurological and psychiatric diseases (such as depression, Alzheimer's disease, etc.) [1].
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