1 Result for "

HCC1970

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HCC1970" in MCE Product Catalog:

Cat. No.: HY-173060
CAS No.: 3093367-23-5
Target:  

ERK Apoptosis Autophagy

Research Areas:  

Cancer

ERK1/2 inhibitor 13 (Compound 21y) is the orally active inhibitor for ERK that inhibits ERK1 and ERK2 with IC50 of 91.71 nM and 97.87 nM. ERK1/2 inhibitor 13 inhibits the proliferation of MCF-7, 4T1, MDA-MB-468, and HCC1970 (IC50 of 0.67, 2.76, 2.15 and 1.68 μM), inhibits the cancer cell migration, induces apoptosis and autophagy in MCF-7. ERK1/2 inhibitor 13 exhibits antitumor and anti-metastatic effect in 4T1 xenograft mouse model .
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