1 Result for "

HDAC-IN-46

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HDAC-IN-46" in MCE Product Catalog:

Cat. No.: HY-150597
CAS No.: 2562386-85-8
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

HDAC-IN-46 (compound 12c) is a potent HDAC inhibitor with an IC50 value of 0.21 μM and 0.021 μM for HDAC1 and HDAC6, respectively. HDAC-IN-46 upregulates p-p38, and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 induces significant G2 phase arrest and apoptosis. HDAC-IN-46 can be used for researching triple-negative breast cancer (TNBC) .
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