1 Result for "

HFPO-TA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HFPO-TA" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W081067
CAS No.: 13252-13-6
Synonyms: HFPO-DA
Target:  

PPAR

Research Areas:  

Infection

Perfluoro (2-methyl-3-oxahexanoic) acid (HFPO-DA) is an orally active PPARα agonist with an EC50 of 2.1 μM for human PPARα. Perfluoro (2-methyl-3-oxahexanoic) acid induces peroxisome proliferation and increases the levels of proinflammatory mediators. It impairs intestinal barrier function and disrupts cecal flora balance. Perfluoro (2-methyl-3-oxahexanoic) acid is applicable to research related to developmental toxicity, hepatotoxicity and intestinal toxicity .
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