1 Result for "

HI042

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HI042" in MCE Product Catalog:

Cat. No.: HY-175473
CAS No.: 898168-15-5
Target:  

FLT3 Apoptosis

Research Areas:  

Cancer

HI042 is a FMS-like Tyrosine Kinase 3 (FLT3) inhibitor. HI042 shows IC50 values of 0.62 μM for MOLM-13, 0.33 μM for MV4-11, and 0.89 μM for OCI-AML3 cells. HI042 selectively reduces the viability of FLT3-internal tandem duplication (FLT3-|TD) mutations-positive cell lines, induces apoptosis, disrupts cell cycle progression, and diminishes the clonogenic potential. HI042 can be used for the research of acute myeloid leukemia (AML) .
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