1 Result for "

HL23

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HL23" in MCE Product Catalog:

Cat. No.: HY-155248
CAS No.: 1448355-15-4
Purity:  98.40%
Target:  

HDAC

Research Areas:  

Cancer

HL23 is a histone deacetylase (HDAC) inhibitor with activity against hepatocellular carcinoma (HCC). HL23 enhances acetylation of the TXNIP promoter and upregulates TXNIP expression, thereby mediating potassium channel activity and triggering TXNIP-dependent potassium deprivation. HL23 inhibits HCC progression and metastasis and has a synergistic effect with Sorafenib (HY-10201) and is more potent than Sorafenib+Vorinostat (HY-10221) .
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