1 Result for "

HMPL-504

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HMPL-504" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-15959
CAS No.: 1313725-88-0
Synonyms: Volitinib; HMPL-504; AZD-6094
Target:  

c-Met/HGFR

Research Areas:  

Cancer

Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC50 s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity .
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