1 Result for "

HPOB

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HPOB" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-19747
CAS No.: 1429651-50-2
Target:  

HDAC Apoptosis

Research Areas:  

Cancer

HPOB is a highly potent and selective inhibitor of HDAC6 with an IC50 of 56 nM. HPOB displays >30 fold less potent against other HDACs. HPOB enhances the effectiveness of DNA-damaging anticancer agents in transformed cells but not normal cells. HPOB does not block the ubiquitin-binding activity of HDAC6 .
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