2 Results for "

Hepcidin modulation

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Hepcidin modulation" in MCE Product Catalog:

Cat. No.: HY-P11260
CAS No.: 3051556-89-6
Research Areas:  

Metabolic Disease

MD5 is a selective TMPRSS6 mimetic peptide inhibitor with an IC50 for recombinant human TMPRSS6 protein of 22 nM and a Ki of 3.4 nM. MD5 exhibits the significantly reduced inhibitory effect on Matriptase, with an IC50 of 352 nM and a Ki of 99.2 nM. MD5 exhibits good target specificity and only has a weak inhibitory effect on thrombin (Thrombin), with Ki of 120 nM. MD5 demonstrates good initial drugability and can be used for the study of iron overload diseases (such as hereditary hemochromatosis, β-thalassemia) .
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Cat. No.: HY-P3494B
Target:  

Hepcidin Bacterial

Research Areas:  

Infection Inflammation/Immunology

Hepcidin-25 (human) TFA is an iron metabolism modulator and Antimicrobial agent. Hepcidin-25 (human) TFA shows anti-inflammatory and anti-bacterial activity via modulation of iron-mediated oxidant injury .
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