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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
HiBit-BRD4
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "HiBit-BRD4" in MCE Product Catalog:
Cat. No.: HY-170900
Research Areas:
SJ44236 is a BET PROTAC degrader with activity against BRD2, BRD3 and BRD4 (DC50 = 127 pM). SJ44236 induces ubiquitination and proteasomal degradation by forming a ternary complex with BET proteins and CRBN-DDB1. SJ44236 downregulates c-Myc, upregulates p53 and reduces cancer cell viability. SJ44236 can be used for the research of leukemia and medulloblastoma .
Cat. No.: HY-157426
CAS No.: 3093737-33-5
Target:
Research Areas:
PROTAC BRD4 Degrader-50 is a BRD4 PROTAC degrader with a DC50 of 11.4 nM (HEK293). PROTAC BRD4 Degrader-50 induces BRD4 degradation via the proteasome and CRBN. PROTAC BRD4 Degrader-50 is applicable to cancer research .
Cat. No.: HY-184455
Target:
Research Areas:
PROTAC BRD4 Degrader-47 is a heterobifunctional PROTAC that selectively degrades BRD4 in a SYVN1-dependent manner, with a DC50 of 0.93 μM. PROTAC BRD4 Degrader-47 can be used in cancer-related research such as breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
