2 Results for "

I-Ag7 MHC class II molecules

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "I-Ag7 MHC class II molecules" in MCE Product Catalog:

Cat. No.: HY-P1745
CAS No.: 163364-16-7
Synonyms: Insulin B chain (9-23)
Target:  

MHC Insulin Receptor IFNAR

Research Areas:  

Inflammation/Immunology

InsB (9-23) (Insulin B chain (9-23)) is an HLA-DQ8-restricted insulin B-chain peptide composed of amino acid residues 9-23. InsB (9-23) serves as a major MHC II class-restricted antigen. InsB (9-23) supports the recognition and activation of T cells, stimulates the secretion of IFN-γ and cytokines, and induces cross-reactive immune responses. InsB (9-23)-specific CD4 T cells can initiate diabetes . InsB (9-23) can be used in research related to type 1 diabetes and autoimmune diabetes .
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Cat. No.: HY-P2525
CAS No.: 245124-26-9
Target:  

MHC

Research Areas:  

Inflammation/Immunology

GAD65 (206-220) is glutamic acid decarboxylase (GAD) 65-derived peptide, corresponding to residues 180-188. GAD65 is presented to T cells in association with I-Ag7 MHC class II molecules and a major pancreatic antigens targeted by self-reactive T cells in type I diabetes mellitus .
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