2 Results for "

IAXO

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IAXO" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-125171
CAS No.: 1115270-63-7
Purity:  ≥98.0%
Research Areas:  

Inflammation/Immunology

IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development .
loading...
    loading...
Cat. No.: HY-129684
CAS No.: 1202388-64-4
IAXO-101 iodide is a TLR4/CD14 blocker. IAXO-101 iodide can inhibit the innate immune pathway of CD14. IAXO-101 iodide is capable of improving the recording performance of intracortical microelectrodes in mice. IAXO-101 iodide can also partially alleviate fetal growth restriction, placental vascular damage, and reduce the level of the inflammatory factor TNF-α in pregnant mice infected with malaria. IAXO-101 iodide can be used in the research of gestational malaria and inflammatory diseases .
loading...
    loading...