1115270-63-7
Chemical Structure
IAXO-102
- CAS No.: 1115270-63-7
- Formula:C35H71NO5
- Molecular Weight:585.94
IUPAC Name: (2R,3R,4S,5R,6S)-2-(aminomethyl)-6-methoxy-4,5-bis(tetradecyloxy)tetrahydro-2H-pyran-3-ol
InChIKey: DJVFNDPRLMVKKO-KJQSSVQNSA-N
SMILES: CCCCCCCCCCCCCCO[C@@H]1[C@H]([C@@H]([C@@H](CN)O[C@@H]1OC)O)OCCCCCCCCCCCCCC
Biological Activity: IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development[1].
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IAXO-102 | 98.0% | IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. IAXO-102 inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development. | ||||||||||||||||||||
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Keywords