2 Results for "

IBI334

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IBI334" in MCE Product Catalog:

Cat. No.: HY-P991092

Target:  

EGFR CD276/B7-H3

Research Areas:  

Cancer

IBI-334 is a bispecific B7-H3 and EGFR antibody. IBI-334 has an EGFR arm for signal blockage and is coupled with a fine-tuned B7-H3 arm with optimal affinity and binding domain. IBI-334 shows antibody-mediated cell cytotoxicity (ADCC) effects. IBI-334 has a wide range of applications in many EGFR-driven solid tumors .
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Cat. No.: HY-P991092A

Target:  

EGFR CD276/B7-H3

Research Areas:  

Cancer

IBI-334 (FUT8-KO) is a bispecific B7-H3 and EGFR antibody that has knocked out the fucosyltransferase 8 gene (FUT8). IBI-334 (FUT8-KO) has an EGFR arm for signal blocking and is coupled with a fine-tuned B7-H3 arm with the best affinity and binding domain. IBI-334 (FUT8-KO), compared to IBI-334 (HY-P991092), has enhanced antibody-mediated cytotoxicity (ADCC) effect. IBI-334 (FUT8-KO) has wide applications in many EGFR-driven solid tumors .
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