1 Result for "

IDEC114

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IDEC114" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99293
CAS No.: 357613-77-5
Synonyms: IDEC 114; Anti-Human CD80 Recombinant Antibody

Target:  

CD28 Apoptosis

Research Areas:  

Cancer

Galiximab (IDEC-114) is a primatized monoclonal IgG1 antibody targeting CD80. Galiximab variable regions are primatized, and the constant regions are humanized. Galiximab induces antibody-dependent cellular cytotoxicity by blocking CD80-CD28 binding. Galiximab has antitumor activity and can induce apoptosis in tumor cells. Galiximab can be used in the research of relapsed Hodgkin lymphoma and solid tumors .
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