1 Result for "

IGM8444

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IGM8444" in MCE Product Catalog:

Cat. No.: HY-P990901
CAS No.: 2796349-94-3
Synonyms: IGM-8444

Target:  

TNF Receptor Apoptosis

Research Areas:  

Cancer

Aplitabart (IGM-8444) is a pentameric IgM death receptor 5 (DR5) agonist antibody with a KD of 85 nM and an apparent affinity of 11 pM. Aplitabart induces DR5 multimerization, thereby triggering cancer cell apoptosis via the extrinsic apoptotic pathway apoptosis. Aplitabart is applicable to cancer-related research such as colorectal cancer and gastric cancer .
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