2 Results for "

INS1-E

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "INS1-E" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P10769
CAS No.: 2209854-03-3
Target:  

AMPK Apoptosis

Research Areas:  

Metabolic Disease

MOTS-c (mouse) is a mitochondrial-derived polypeptide that can be used to regulates pancreatic cell function. MOTS-c (mouse) reduces insulin secretion and expression in INS-1E cells, and enhances glucagon secretion and expression in αTC-1 cells. MOTS-c (mouse) decreases the apoptosis in INS-1E and αTC-1. MOTS-c (mouse) counteracts diet-induced obesity and insulin resistance through AMPK activation [1].
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1
1 Cited Publications
Cat. No.: HY-13529
CAS No.: 1234703-40-2
Purity:  ≥98.0%
Synonyms: LY2608204; SY-004
Target:  

Glucokinase

Research Areas:  

Metabolic Disease

Globalagliatin (LY2608204) is an orally active glucokinase (GK) activator with an EC50 of 42 nM. Globalagliatin also stimulates glucose metabolism in rat insulinoma INS1-E cells with an EC50 of 579 nM. Globalagliatin targets both pancreatic β-cells and hepatocytes. Globalagliatin is promising for research of type 2 diabetes [1] .
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