1 Result for "

IPI-269609

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IPI-269609" in MCE Product Catalog:

Cat. No.: HY-13654
CAS No.: 878204-96-7
Target:  

Smo Hedgehog

Research Areas:  

Cancer

IPI-269609 is an orally effective Smoothed (SMO) inhibitor that targets the Hedgehog (Hh) signaling pathway. IPI-269609 specifically reduces the ALDH-bright (high aldehyde dehydrogenase activity) cell subset, which is considered the "cancer stem cells" in pancreatic cancer. IPI-269609 significantly inhibits the migration and colony formation of pancreatic cancer cells. IPI-269609 effectively inhibits pancreatic cancer metastasis in a mouse model. IPI-269609 can be used for pancreatic cancer research .
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